How ‘killer’ T cells Сould Boost COVID Immunity In Face Of New Variants

Consumption of a Mediterranean-Like Dietary Pattern Induces Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses.
Scientists find that T cells protect against COVID-19 better than antibodies.Chinese Scientists Determine the Role of Cellular Immunity in Protecting Against COVID-19.

Chinese scientists have carried out digital simulations. The results showed that T cells play an even more important role in fighting the coronavirus than specific antibodies. The article was published in the journal Royal Society Open Science.
https://royalsocietypublishing.org/doi/10.1098/rsos.211606
T lymphocytes, or T cells, are essential elements of the acquired immune response. These are white blood cells that react to foreign substances such as viruses that enter the body. With their submission, the immune system starts the mechanisms of recognition and destruction of cells carrying foreign antigens.
Based on accurate descriptions of clinical data from hundreds of patients with COVID-19, researchers from Peking University and the Chinese Academy of Medical Sciences have built a mathematical model to find out what role these cells play in preventing severe disease and death from coronavirus infection.
The results of quantitative modeling of cellular responses have shown that the deterioration of T-cell antiviral and anti-inflammatory immunity can become critical in the case of COVID-19 disease. It turned out that compared to antibodies, T cells play a more important role in clearing the SARS-CoV-2 virus. Concerning patients with a mild form of the disease, they destroy up to 96.5 percent of viral particles.
In addition, anti-inflammatory responses, inhibition of cytokines, and rate of tissue repair correlate with the number of T cells that were significantly suppressed in fatal patients. Simulations show that a lack of T cells leads to inflammation and the development of a cytokine storm, one of the leading causes of death from COVID-19.
The authors hope that their discovery will launch a new direction in the fight against COVID-19, based on increasing the number of T cells.
Consumption of a Mediterranean-Like Dietary Pattern Induces Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses.